Sophie is recovered, and I can put away the benedryl. It was caused by Mountain Fresh scent Tide! After the new washing machine was installed, we washed her futon, also several blankets. She's always either in the living room, on the couch wrapped in a blanket, or in the kitchen laying on her futon. Not a real active dog! I prefer Arm & Hammer laundry soap, but Bob likes Tide - so we usually have a jug of each around. Generally though we have the unscented varieties, since I am somewhat sensitive to perfumes and dyes. But not this time. So I re-washed everything in unscented Arm & Hammer. She still has some large scabby patches from where she scratched herself raw.